Objectives and disease focus

This partnership, which started on March 1st 2015, comprises Universitites, Hospitals, Pharmaceutical Companies, Biotechs and Disease Foundations working towards:

  1. Generating protein based research tools (e.g. structures, assays)
  2. Generating chemical and antibody probes
  3. Using patient-cell derived assays for target definition and validation
  4. Making all reagents and knowledge available through Open Source
  5. Significantly contribute to understanding of complex disease systems
  6. Promote drug discovery and development

 

Research tools

University of Oxford
  • Target Selection
  • Protein Production
  • Biochemical and Biophysical Assasys
  • 3D Structures
  • Chemical Biology
Karolinska  Intitutet
  • Protein Production
  • Antibody Generation

ETH Zurich

  • Functional Proteomics (mass spectrometry)

  • Target Selection
  • Chemical Biology

Disease focus

University of Oxford

Inflammatory diseases that induce bone and cartilage damage:

  • Fibrosis (of e.g. hand, lung and and liver)
  • Ankylosing spondylitis (AS)
  • Fibrodysplasia ossificans progressiva (FOP, stone man syndrome)
Karolinska  Intitutet

Systemic inflammatory autoimmune diseases (SIADs) with increased with common co-morbidities such as cancer and cardiovascular disease:

  • Systemic Lupus Erythematosus (SLE)
  • Idiopathic myositis
  • Systemic sclerosis (SSc)
  • Sjogren´s syndrome (SS)